At the Bench

People living in disadvantaged neighborhoods are more likely to experience repeat observation stays at hospitals, which may lead to costly medical bills without a means to pay them, according to a recent study from UW-Madison researchers. This research, which included lead author Ann Sheehy, MD, MS, associate professor, Hospital Medicine...
1. Badar T, Szabo A, Dinner S, Liedtke M, Burkart M, Shallis RM, Yurkiewicz IR, Kuo E, Khan MA, Balasubramanian S, Yang J, Hefazi M, Podoltsev N, Patel A, Curran E, Wang A, Arslan S, Aldoss I, Siebenaller C, Mattison RJ, Litzow MR, Wadleigh M, Advani AS, Atallah E. Sequencing...
Recognizing that where people live affects their health, Jennifer Weiss, MD, MS, associate professor, Gastroenterology and Hepatology, and partners at the University of Wisconsin Health Innovation Program (HIP) have developed a more nuanced way to identify health disparities in Wisconsin’s rural and urban areas. Their work is reflected in “WCHQ...
1. Akuthota P, Busse WW. How Sex and Age of Asthma Onset Influence Difficult Asthma Heterogeneity. J Allergy Clin Immunol Pract. 2020;8(10):3407-3408. 2. Alzoubi B, Kharel A, Osman F, Aziz F, Garg N, Mohamed M, Djamali A, Mandelbrot DA, Parajuli S. Incidence, Risk Factors, and Outcomes of Post-Transplant Erythrocytosis After...
Last spring, when researchers began pivoting their studies to COVID-19 research, Miriam Shelef, MD, PhD, associate professor, Rheumatology, saw the need for a biological repository of blood samples from individuals who have recovered from the virus. Dr. Shelef started sending emails to see if anyone at UW–Madison was banking plasma...
Scientists at the University of Wisconsin–Madison, including David Andes, MD, professor, Infectious Disease, have discovered a new antifungal compound found in the microbiome of a sea squirt from the Florida Keys. The antifungal, which the scientists named turbinmicin, efficiently targets multi-drug–resistant strains of deadly fungi without toxic side effects in...
Matthew Merrins, PhD, assistant professor, Endocrinology, Diabetes and Metabolism, recently led a study on insulin secretion that has changed previous thinking, and could open up doors for new research to be done on diabetes treatments. Dr. Merrins and his colleagues look at activating the enzyme, pyruvate kinase, as a way...
1. Abulizi A, Cardone RL, Stark R, Lewandowski SL, Zhao X, Hillion J, Ma L, Sehgal R, Alves TC, Thomas C, Kung C, Wang B, Siebel S, Andrews ZB, Mason GF, Rinehart J, Merrins MJ, Kibbey RG. Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health. Cell Metab...
Shivani Garg, MD, MS, assistant professor, Rheumatology, was the lead author on a study that found Black patients with lupus in the U.S. have a three times higher risk of stroke and a 24-fold higher risk for ischemic heart disease. The researchers also identified risk factors that were predictive of...
By tracking COVID-19 virus mutation, a study published in Nature Communications that includes co-authors Nasia Safdar, MD, PhD, and Caitlin Pepperell, MD, FRCPC, shows the success that stay-at-home orders had in preventing the spread of the virus. According to an analysis of the genome sequences of virus samples collected from...