At the Bench

Through the work of the UW-Madison Stem Cell and Regenerative Medicine Center, UW has remained at the forefront of the stem cell field - which is celebrating a 20-year milestone of the first derivation of human embryonic stem cells by James Thomson, VMD, PhD , professor, Department of Cell and...
A multi-institutional clinical study facilitated by the Big Ten Cancer Research Consortium is aimed at evaluating a combination of radiation and immunotherapy for treating advanced bladder cancer. Hamid Emamekhoo, MD , assistant professor (CHS), Hematology, Medical Oncology and Palliative Care, explained why the consortium aids recruitment. Only a subset of...
William Busse, MD , professor, Allergy, Pulmonary and Critical Care Medicine, commented in an article published by MD Magazine on a phase 3 clinical trial that he is leading. The BORA trial is investigating the long-term efficacy of benralizumab for treatment of asthma. Results indicate that the medication was remained...
Image (above): A scanning electron micrograph shows Candida albicans yeast (elongated structure at left) building an antifungal drug-resistant biofilm structure by secreting small, spherical extracellular vesicles (arrows) that deliver payloads of biofilm polymers to the extracellular matrix. The pathogenic yeast Candida albicans has a clinically frustrating habit: when it colonizes...
The Wisconsin Registry for Alzheimer’s Prevention (WRAP) has been awarded a five-year, $19 million renewal grant from the National Institutes of Health to enable in-depth study of molecular hallmarks of the disease in the brain and spinal fluid. The additional funding will expand capacity for in-depth tests for biomarkers that...
Rheumatoid arthritis is a painful and debilitating disease in which the body's immune system becomes dysfunctional, inappropriately attacking joint tissue and causing inflammation. A new research study is focusing on several as-yet-unsolved mysteries in the immunology of rheumatoid arthritis. Miriam Shelef, MD, PhD (pictured above), assistant professor, Rheumatology, has been...
Nasia Safdar, MD, PhD (pictured above), professor, Infectious Disease and vice chair for research, has been awarded $5.1M over 5 years (U01 award) from the National Institutes of Health-National Institute of Allergy and Infectious Diseases for a proposal entitled, "Fecal Microbiota Transplant for C. difficile Infection in Solid Organ Transplant...
Dudley Lamming, PhD (pictured above and at upper right), assistant professor, and Matthew Merrins, PhD (pictured at lower right), assistant professor, both of Endocrinology, Diabetes and Metabolism, have been awarded $1.9M over 5 years (R01 award) from the National Institutes of Health-National Institute on Aging for a proposal entitled, "Comparative...
Barbara Bendlin, PhD (pictured above), associate professor, Geriatrics and Gerontology, Bradley Christian, PhD , professor, Department of Medical Physics, and Sterling Johnson, PhD , professor, Geriatrics and Gerontology, have been awarded $3.7M over 5 years (R01 award) from the National Institutes of Health-National Institute on Aging for a proposal entitled,...
Timothy Baker, PhD , emeritus professor, General Internal Medicine and research director, UW Center for Tobacco Research and Intervention, and James Stein, MD , professor, Cardiovascular Medicine, have been awarded $1.8M over 4 years (R01 award) from the National Institutes of Health-National Heart, Lung, and Blood Institute for a proposal...