Research - Recent Publications

Image (above): A scanning electron micrograph shows Candida albicans yeast (elongated structure at left) building an antifungal drug-resistant biofilm structure by secreting small, spherical extracellular vesicles (arrows) that deliver payloads of biofilm polymers to the extracellular matrix. The pathogenic yeast Candida albicans has a clinically frustrating habit: when it colonizes...
2018 was been a productive year for researchers in the Department of Medicine. How productive? Members published at least 452 peer-reviewed research and scholarly articles – more than one per day. And that’s almost certainly an underestimate. Some journals will still be populating article from 2018 in databases for the...
Research led by Nilay Kumar, MD (pictured at right), clinical assistant professor, Hospital Medicine, found a strong seasonal pattern to Google search queries related to cardiovascular disease topics . The team searched Google Trends for popular cardiovascular disease search terms, assessing relative search volumes for a 10-year period in the...
Members of the Division of Cardiovascular Medicine were among the 20,000 people attending the 2018 American Heart Association Scientific Sessions on November 10-12, 2018 in Chicago, Illinois. The Badgers contingent left a strong impression, according to James Stein, MD , professor, Cardiovascular Medicine and Robert Turell Professor of Cardiovascular Research....
A multi-site prospective study led by J. Scott Ferguson, MD , professor (CHS), Allergy, Pulmonary and Critical Care Medicine, found that even when guidelines were followed for cleaning and disinfecting flexible bronchoscopes, residual contamination remained in all 24 instruments analyzed. The authors recommend a shift toward the use of sterilized...
Observation status - in which hospitalized Medicare beneficiaries are classified as outpatients for billing status – posed an intractable problem for health services and care research. Despite observation stay policies being in place for many years, there wasn’t a standard method that health services researchers could rely on to identify...
Socio-economic factors can affect health in surprising ways. For example: A doctor prescribes insulin for a diabetic patient, but doesn’t ask if the patient has a refrigerator in which to store it. The patient lives in a neighborhood with substandard housing conditions, and a working refrigerator or electricity isn’t a...
In a study published in Aging Cell , researchers at the University of Wisconsin–Madison show that mice making too much of a human protein called AT-1 show signs of early aging and premature death, which are also symptoms of the human disorder progeria. Researchers were able to reverse the signs...
A new study of how relationships affect one's ability to quit smoking focused on analyzing social interactions of smokers. Researchers found that people who are "socially disconnected" (defined as having little social interaction, low levels of stress, and low exposure to social cues about environmental smoking cues) have the highest...
As a public health measure, HIV testing is an essential strategy. Undiagnosed HIV infection is thought to account for one- third of HIV transmissions in the United States, and the Centers for Disease Control and Prevention (CDC) estimates that 15 percent of individuals living with HIV are unaware of their...